Product Description

NLGN3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60735-50, BS60735-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain . Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3 . Neuroligins are expressed in excitatory neuronal synaptic clefts . Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins . Neuroexin 1∫ binds to the EF-hand domain of Neuroligin 1 and requires calcium ion . Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses .

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Neuroligin-3, Gliotactin homolog, NLGN3, KIAA1480, NL3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human NLGN3

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: NLGN3 polyclonal antibody detects endogenous levels of NLGN3 protein.

Molecular Weight: ~ 94 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NZ94

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only