Product Description

NLRC3 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90946-50, BS90946-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q7RTR2(Human) Q5DU56(Mouse)

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ICC IHC FC

All Applications: WB:1:500-1:2000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:200

Background: NLRC3, short for NOD-like receptor family CARD domain containing 3, is an intracellular protein that plays a role in the immune system. It was previously known as nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3 (NOD3) and CLR16.2. NLRC3 inhibits the activity of T cells. Decreases the transcription of genes that are normally up-regulated after T-cell stimulation. Delays degradation of NFKBIA/IKBA.

Purification and Purity: Peptide affinity purified.

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: NLRC3 polyclonal antibody detects endogenous levels of NLRC3 protein.

Bioworld Molecular Weight: 120 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of NLRC3 on human thymus tissue lysates using anti-NLRC3 antibody at 1/500 dilution., ICC staining NLRC3 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: CLR16.2, NLRC3, NOD3, CARD15-like, CARD15-like protein, Caterpiller 16.2, Caterpiller protein 16.2, CLR16.2, FLJ00348, NLR family CARD domain containing 3, Nlrc3, NLRC3, NOD-like receptor C3, NOD3, NOD3 protein, Nucleotide-binding oligomerization domain protein 3, Nucleotide-binding oligomerization domain protein 3 caterpiller 16.2, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3, Protein NLRC3,

Immunogen: Peptide

Conjugate: Unconjugated

Modification: Unmodified