NLRP10 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-16648-60, E-AB-16648-120, E-AB-16648-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: NLRP10
Target Synonym: CLR11.1; NACHT; leucine rich repeat and PYD containing 10; NACHT; LRR and PYD domains containing protein 10; NACHT; LRR and PYD domains-containing protein 10; NAL10; NALP10; NLR family; pyrin domain containing 10; Nlrp10; NOD8; Nucleotide-binding oligomerization domain protein 8; Nucleotide-binding oligomerization domain; leucine rich repeat and pyrin domain containing 10; PAN5; PYNOD
Research Areas: Cell biology, Immunology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q86W26
Background: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
Concentration: 1.2 mg/mL
Immunogen: Synthetic peptide of human NLRP10
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only