Product Description

NM23-H1 (Y52) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3552-50, BS3552-100

Sizes: 50µl, 100µl

Swiss-Prot: P15531

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: NM23-H1 (Y52) polyclonal antibody detects endogenous levels of NM23-H1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of NM23-H1 (Y52) polyclonal antibody at 1:500 dillution
Lane 1: U-87MG whole cell lysate (40μg)
Lane 2: HepG2 whole cell lysate (40μg)
Lane 3: BV2 whole cell lysate (40μg)
Lane 4: C6 whole cell lysate (40μg), Immunohistochemistry (IHC) analyzes of NM23-H1 (Y52) pAb in paraffin-embedded human brain tissue.

Bioworld Molecular Weight: ~ 20 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; NM23-H1; Tumor metastatic process-associated protein; NME1; NDPKA; NM23

Immunogen: Synthetic peptide, corresponding to amino acids 20-70 of Human NM23-H1.

Conjugate: Unconjugated

Modification: Unmodified