NM23-H2 rabbit pAb - ES6396

NM23-H2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6396-50, ES6396-100

Citations, Manuals and MSDS Available upon request.

Background: Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010],

Alternate Name: NME2; NM23B; Nucleoside diphosphate kinase B; NDK B; NDP kinase B; C-myc purine-binding transcription factor PUF; Histidine protein kinase NDKB; nm23-H2

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human NM23. AA range:91-140

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 23kD

Human Gene ID: 4831/654364

Human SWISS Prot NO: P22392

Subcellular Location: Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Colocalizes with ITGB1 and ITGB1BP1 at the edge or peripheral ruffles and lamellipodia during the early stages of cell spreading on fibronectin or collagen but not on vitronectin or laminin substrates.; [Isoform 1]: Cytoplasm. Cytoplasm, perinuclear region. Nucleus.; [Isoform 3]: Cytoplasm. Cytoplasm, perinuclear region. Nucleus.

Research Use Only