NMDAR2A Monoclonal Antibody-MB11313

NMDAR2A Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11313-50, MB11313-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P35436

Host: Rabbit

Reactivity: Mouse,Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+. Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kinetics than channels formed by GRIN1 and GRIN2B . Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of NMDAR2A in mouse lungLysates using NMDAR2A antibody.

Bioworld Molecular Weight: Calculated MW: 165 kDa; Observed MW: 165 kDa

Specificity: IgG

Alternative Name: NR2A; GluN2A; NMDAR2A; GluRepsilon1

Immunogen: Recombinant protein of mouse NMDAR2A

Conjugate: Unconjugated

Modification: Unmodified