NOD1 Rabbit Polyclonal Antibody - BT-AP03837

NOD1 Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03837-20, BT-AP03837-50, BT-AP03837-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD)| a centrally located nucleotide-binding domain (NBD)| and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling| LRRs participate in protein-protein interactions| and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5andapos; UTR have been described| but the full-length nature of these variants has not been determined.

Research Areas: Cell biology

Target Protein: NOD1

Applications: WB

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: NOD1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9Y239; Mouse: Q8BHB0

Synonyms: NOD1; Nucleotide-binding oligomerization domain-containing protein 1; Caspase recruitment domain-containing protein 4

GeneID: Human: 10392; Mouse: 107607

Research Use Only