Nogo B Receptor Monoclonal Antibody-MB11316

Nogo B Receptor Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11316-50, MB11316-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q96E22

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394, PubMed:25066056, PubMed:28842490). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator (PubMed:16835300).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Nogo B receptor in K562, 3T3, HelaLysates using Nogo B Receptor antibody.

Bioworld Molecular Weight: Calculated MW: 33 kDa; Observed MW: 33 kDa

Specificity: IgG

Alternative Name: NgBR; MRD55; CDG1AA; C6orf68; TANGO14; MGC:7199

Immunogen: A synthetic peptide of human Nogo B receptor

Conjugate: Unconjugated

Modification: Unmodified