Product Description

Nova1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65682-50, BS65682-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Nova-1 and Nova-2 are members of a superfamily of protein regμlators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1, 2). Nova proteins, normally sequestered in the central nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3, 4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regμlating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5).

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Cow

Host: Rabbit

Applications: WB

Alternate Names: Neuro oncological ventral antigen 1, Neuro-oncological ventral antigen 1, NOVA 1, Nova-1, Nova1, NOVA1_HUMAN, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, RNA binding protein Nova 1, RNA-binding protein Nova-1, Ventral neuron specific protein 1, Ventral neuron-specific protein 1.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human Nova1

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: Nova1 Polyclonal Antibody detects endogenous levels of Nova1 protein.

Molecular Weight: 52 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P51513

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only