NPHS2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-16657-60, E-AB-16657-120, E-AB-16657-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: NPHS2
Target Synonym: Nephrosis 2; idiopathic; steroid resistant (podocin); nephrosis 2; idiopathic; steroid resistant; NPHS2; NPHS2 gene; PDCN; PODO; Podocin; SRN1
Research Areas: Cancer, Cell biology, Signal transduction, Tags and Cell markers
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9NP85
Background: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
Concentration: 1.4 mg/mL
Immunogen: Synthetic peptide of human NPHS2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only