Product Description

NPPA Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS6680-50, BS6680-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P01160

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB 1:500 - 1:2000

Background: Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. ANP, BNP, and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage. The genes which encode for ANP and BNP map to human chromosome 1p36.2. The gene which encodes for CNP maps to human chromosome 2q24-qter.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NPPA polyclonal antibody detects endogenous levels of NPPA protein.

Bioworld Molecular Weight: ~ 16 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of PC-3 cell lines, using NPPA antibody.

Alternative Name: ANF; ANF; ANP; ATFB6; Atrial natriuretic factor; Atrial natriuretic peptide; Atriopeptin; Cardionatrin; CDD-ANF; CDP; Natriuretic peptide A; Natriuretic peptide precursor A; Natriuretic peptides A; NPPA; PND; Prepronatriodilatin; Pronatriodilatin;

Immunogen: Recombinant full length Human NPPA.

Conjugate: Unconjugated

Modification: Unmodified