Product Description

NPPC Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60381-50, BS60381-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Natriuretic peptides comprise a family of 3 structurally related molecμles: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) . ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control . ANP, BNP, and CNP are highly homologous within the 17-residue ring structure formed by an intramolecμlar disμlfide linkage . The genes which encode for ANP and BNP map to human chromosome 1p36.2 . The gene which encodes for CNP maps to human chromosome 2q24-qter .

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: C-type natriuretic peptide, Cleaved into the following 3 chains:CNP-22, CNP-29, CNP-53, NPPC, CNP2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human NPPC.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: NPPC polyclonal antibody detects endogenous levels of NPPC protein.

Molecular Weight: ~ 7 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P23582

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only