NPY rabbit pAb - ES6406

NPY rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6406-50, ES6406-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014],

Alternate Name: NPY; Pro-neuropeptide Y

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: IHC-p 1:100-500，WB 1:500-2000, ELISA 1:5000-20000

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human NPY. AA range:45-94

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 4852

Human SWISS Prot NO: P01303

Subcellular Location: Secreted. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle.

Research Use Only