NQO1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA20598-50, RA20598-100 Citations, Manuals and MSDS Available upon request. Background: NAD (P) H quinone dehydrogenase 1 (NQO1) Homo sapiens This gene is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) . Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Alternative Names: NQO1; DIA4; NMOR1; NAD (P) H dehydrogenase [quinone] 1; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD (P) H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1 Applications: WB; ELISA Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 1728 Protein MW (KDa): 31 SWISS: P15559 Source: Rabbit Research Use Only