NQO1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA20598-50, RA20598-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: NAD (P)H quinone dehydrogenase 1 (NQO1) Homo sapiens This gene is a member of the NAD (P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: WB, ELISA Alternate Names: NQO1, DIA4, NMOR1, NAD (P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD (P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1 Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Molecular Weight: 31 Protein Molecular Weight (kDa): 31 Storage: -20°C/1 year Human Gene ID: 1728 Human SwissProt Number: P15559 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only