Product Description

NR0B2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33622-50, RA33622-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: nuclear receptor subfamily 0 group B member 2 (NR0B2) Homo sapiens The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 28

Protein Molecular Weight (kDa): 28

Storage: -20°C/1 year

Human Gene ID: 8431

Human SwissProt Number: Q15466

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only