NR2C2 Monoclonal Antibody - BT-MCA2034

NR2C2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2034-50, BT-MCA2034-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]

Research Areas: Epigenetics and nuclear signaling

Target Protein: NR2C2

Applications: FCM

Clonality: Monoclonal

Clone ID: 8H11D4

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: NR2C2

Immunogen: Purified recombinant fragment of human NR2C2 (AA: 62-356) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 65.4kDa

UniProt Accession: P49116

Synonyms: TR4, TAK1

GeneID: 7182

Research Use Only