Product Description

NR6A1 Polyclonal Antibody

Catalogue Numbers: GCP62-50, GCP62-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: Q15406

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1:2000~1:5000

Background: GCNF (Germ Cell Nuclear Factor), also known as NR6A1 (Nuclear Receptor Subfamily 6 Group A member), is an orphan member of the nuclear receptor gene superfamily. It has been shown to be expressed in the nervous system during development and during specific stages in maturing germ cells of the ovary and testis in the adult, and has probable roles in gametogenesis, neurogenesis, and normal embryonic development during gastrulation. Inactivation of GCNF in mouse results in abnormal posterior development, impaired midbrain development, insufficient closure of the neural tube, and eventual embryonic death. GCNF has been shown to be a repressor of OCT-4 and of the protamine genes and plays a critical role in the control of gene expression during embryogenesis and spermatogenesis.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NR6A1 polyclonal antibody detects endogenous levels of NR6A1 protein.

Extra Notes: Western blot (WB) analysis of NR6A1 polyclonal antibody at 1:2000 dilution
Lane1:Hela whole cell lysate(40ug)
Lane2:HepG2 whole cell lysate(40ug)
Lane3:K562 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Nuclear receptor subfamily 6 group A member 1; Germ cell nuclear factor; GCNF; hGCNF; Retinoid receptor-related testis-specific receptor; RTR; hRTR; NR6A1; GCNF

Immunogen: Synthetic peptide, corresponding to Human NR6A1.

Conjugate: Unconjugated

Modification: Unmodified