Product Description

NRARP Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS75065-50, BS75065-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Downstream effector of Notch signaling. Involved in the regμlation of liver cancer cells self-renewal. Involved in angiogenesis acting downstream of Notch at branch points to regμlate vascμlar density. Proposed to integrate endothelial Notch and Wnt signaling to control stalk cell proliferation and to stablilize new endothelial connections during angiogenesis. During somitogenesis involved in maintenance of proper somite segmentation and proper numbers of somites and vertebrae. Required for proper anterior-posterior somite patterning. Proposed to function in a negative feedback loop to destabilize Notch 1 intracellμlar domain (NICD and downregμlate the Notch signal, preventing expansion of the Notch signal into the anterior somite domain (By similarity.

Category: Primary Antibody

Reactivity: Mouse

Host: Rabbit

Applications: WB

Alternate Names: NRARP

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human NRARP(NP_001004354.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 12kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q7Z6K4

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only