NRBP Polyclonal Antibody - BT-AP12017

NRBP Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12017-20, BT-AP12017-50, BT-AP12017-100

Citations, Manuals and MSDS Available upon request.

Background: Author states that kinase activity observed in PubMed:11956649 may be due to sample contamination. This protein is predicted to be catalytically inactive.,The protein kinase domain is predicted to be catalytically inactive.,May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.,Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,Contains 1 protein kinase domain.,subcellular location:Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.,subunit:Homodimer. Binds to MLF1, recruiting a serine kinase which phosphorylates both itself and MLF1. Phosphorylated MLF1 binds to YWHAZ and is retained in the cytoplasm.,tissue specificity:Ubiquitously expressed in all tissues examined with high levels in the testis.,

Research Areas: Signal transduction

Target Protein: NRBP1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Nuclear receptor-binding protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9UHY1; Mouse: Q99J45

Synonyms: Nuclear receptor-binding protein

GeneID: Human: 29959

Research Use Only