NRBP rabbit pAb - ES10837

NRBP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10837-50, ES10837-100

Citations, Manuals and MSDS Available upon request.

Background: caution:Author states that kinase activity observed in PubMed:11956649 may be due to sample contamination. This protein is predicted to be catalytically inactive., domain:The protein kinase domain is predicted to be catalytically inactive., function:May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family., similarity:Contains 1 protein kinase domain., subcellular location:Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia., subunit:Homodimer. Binds to MLF1, recruiting a serine kinase which phosphorylates both itself and MLF1. Phosphorylated MLF1 binds to YWHAZ and is retained in the cytoplasm., tissue specificity:Ubiquitously expressed in all tissues examined with high levels in the testis.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 58kD

Human Gene ID: 29959

Human SWISS Prot NO: Q9UHY1

Subcellular Location: Cytoplasm, cell cortex. Endomembrane system. Cell projection, lamellipodium. Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.

Research Use Only