Product Description

NRF1 Monoclonal Antibody

Catalogue Numbers: MB66554-50, MB66554-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q16656

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Nuclear respiratory factor 1 (NRF1) was identified as a transcription activator for the gene encoding cytochrome c. It was later found to play a role in the nuclear control of mitochondrial function. PGC-1 induces the expression of NRF1 and NRF2. NRF1, along with the coactivator PGC-1, stimulates the promoter of mitochondrial transcription factor A, which regulates mitochondrial biogenensis and function.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of NRF1 protein.

Extra Notes: Western blot analysis of NRF1 expression in Hela (A), K562 (B), CEM (C), U2OS (D) whole cell lysates.

Bioworld Molecular Weight: ~ 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Nuclear respiratory factor 1; NRF-1; Alpha palindromic-binding protein; Alpha-pal

Immunogen: Purified recombinant human NRF1 protein fragments expressed in E.coli

Conjugate: Unconjugated

Modification: Unmodified