NRXN1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A10066-20, A10066-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+) -dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3, 000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 15kDa/46kDa/161kDa/164kDa/169kDa
Observed Molecular Weight: 162kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 9378
SWISS: P58400/Q9ULB1
Alternate Names: PTHSL2; SCZD17; Hs.22998; NRXN1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Neuroscience, Cell Type Marker, Neuron marker, Synapse marker.
NCBI Alias: NRXN1
Research Use Only