NSE Mouse mAb - EM1066

NSE Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1066-50, EM1066-100

Citations, Manuals and MSDS Available upon request.

Background: Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.

Alternate Name: ENO2, Enolase 2, enolase 2 (gamma, neuronal), Gamma enolase, Neural enolase, Neuron specific enolase

Source: Mouse

Applications: WB, IHC

Dilution: WB 1:2, 000 IHC 1:200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 47kDa

Human Gene ID: 2026

Human SWISS Prot NO: P09104

Subcellular Location: Cytoplasm. Cell membrane.

Research Use Only