NSUN2 Rabbit Polyclonal Antibody - BT-AP11581

NSUN2 Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11581-20, BT-AP11581-50, BT-AP11581-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Research Areas: Epigenetics and nuclear signaling

Target Protein: NSUN2

Applications: WB

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: NSUN2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q08J23; Mouse: Q1HFZ0

Synonyms: NSUN2; tRNA; cytosine;34-C;5-methyltransferase; EC 2.1.1.203; Myc-induced SUN domain-containing protein; Misu; NOL1/NOP2/Sun domain family member 2; Substrate of AIM1/Aurora kinase B; tRNA; cytosine-5--methyltransferase; tRNA methyltransferase 4 homolog; hTrm4

GeneID: Human: 54888; Mouse: 28114

Research Use Only