NTE rabbit pAb - ES4093

NTE rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4093-50, ES4093-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

Alternate Name: PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PNPLA6. AA range:1031-1080

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 150kD

Human Gene ID: 10908

Human SWISS Prot NO: Q8IY17

Subcellular Location: Endoplasmic reticulum membrane; Single-pass type III membrane protein.

Research Use Only