Product Description

Nucleolin Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12160-50, MB12160-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P19338

Host: Rabbit

Reactivity: Human

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Nucleolin in Hela, A549, HL-60Lysates using Nucleolin antibody.

Bioworld Molecular Weight: Calculated MW: 77 kDa; Observed MW: 100 kDa

Specificity: IgG

Alternative Name: C23; Nsr1

Immunogen: A synthetic peptide of human Nucleolin

Conjugate: Unconjugated

Modification: Unmodified