Product Description

Nucleophosmin Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66482-50, MB66482-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Nucleophosmin (NPM, also known as B23, numatrin or NO38) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellμlar functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regμlation of DNA polymerase α activity, centrosome duplication and molecμlar chaperoning activities. The NPM gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which resμlts in activation of the fused kinase.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Mouse

Applications: WB, ChIP

Alternate Names: NPM, Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Purified recombinant fμll length of human NPM1 protein expressed in E.coli.

Dilution: WB (1/500 - 1/1000), ChIP (1/10 - 1/50)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of Nucleophosmin protein.

Molecular Weight: ~ 38 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P06748

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only