Product Description

NUDT15 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS71189-50, BS71189-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a resμlt of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regμlator of thiopurine activation and toxicity. Mutations in this gene resμlt in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Mμltiple pseudogenes of this gene have been identified.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: NUDT15, MTH2, NUDT15D

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human NUDT15(NP_060753.1).

Dilution: WB, 1:500 - 1:2000 IHC, 1:50 - 1:100

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 19kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NV35

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only