NUDT5 Rabbit Polyclonal Antibody - RA33678

NUDT5 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33678-50, RA33678-100

Citations, Manuals and MSDS Available upon request.

Background: This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1：500-2000

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 11164

SWISS: Q9UKK9

Source: Rabbit

Research Use Only