NUMB Polyclonal Antibody - BT-AP06232

NUMB Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06232-20, BT-AP06232-50, BT-AP06232-100

Citations, Manuals and MSDS Available upon request.

Background: Protein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.

Research Areas: Neuroscience

Target Protein: NUMB

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: NUMB Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 70804

UniProt Accession: Human: P49757; Mouse: Q9QZS3; Rat: Q2LC84

Synonyms: NUMB; Protein numb homolog; h-Numb; Protein S171

GeneID: Human: 8650; Mouse: 18222

Research Use Only