Product Description

Nup160 (L424) Polyclonal Antibody

Catalogue Numbers: BS3355-50, BS3355-100

Sizes: 50µl, 100µl

Alternative Name: Nuclear pore complex protein Nup160; 160 kDa nucleoporin; Nucleoporin Nup160; NUP160; KIAA0197; NUP120

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q12769

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG).Nuclear pore complex protein Nup96 (Nup96) is formed by cleavage of a 186 kDa precursor protein. This proteolytic cleavage yields two nucleoporins,Nup98 and Nup96. Nup96 is part of the Nup160 subcomplex in the nuclear pore (which consists of Nup160, Nup133, Nup107 and Nup96). Nup96 plays a major role in the two-way transport across the nuclear pore and is important in RNA export.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Nup160 (L424) polyclonal antibody detects endogenous levels of Nup160 protein.

Bioworld Molecular Weight: ~150 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Nup160 (L424) pAb at 1:2000 dilution
Lane 1: Hela whole cell lysate(20ug)
Lane 2: K562 whole cell lysate(20ug)
Lane 3: The Testis tissue lysate of Mouse(40ug)
Lane 4: The Uterus tissue lysate of Rat(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 400-450 of Human Nup160.

Conjugate: Unconjugated

Modification: Unmodified