NUP214 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A27954-20, A27954-100
Citations, Manuals and MSDS Available upon request.
Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t (6, 9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human
Protein Weight: 214kDa
Observed Molecular Weight: 268KDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 8021
SWISS: P35658
Alternate Names: CAN; CAIN; IIAE9
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:3000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling.
NCBI Alias: NUP214
Research Use Only