Product Description

NUP98 Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11762-50, RA11762-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: nucleoporin 98 (NUP98) Homo sapiens Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of

Reactivity: Human

Host: Mouse

Applications: WB, IP

Alternate Names: 96 kDa nucleoporin, 98 kDa nucleoporin, ADAR2, ADIR2, GLFG-repeat containing nucleoporin, Nuclear pore complex protein Nup96, Nuclear pore complex protein Nup98 Nup96, Nucleoporin 98kD, nucleoporin 98kDa, Nucleoporin Nup96, Nucleoporin Nup98, NUP196, NUP96, Nup98, Nup98-Nup96, NUP98_HUMAN.

Clonality: Monoclonal

Dilution: wb 1:1000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 4928

Protein Molecular Weight（KDa): 98

Molecular Weight: 98

Research Use Only