NVL rabbit pAb - ES3777

NVL rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3777-50, ES3777-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011],

Alternate Name: NVL; Nuclear valosin-containing protein-like; NVLp; Nuclear VCP-like protein

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from NVL . at AA range: 320-400

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 95kD

Human Gene ID: 4931

Human SWISS Prot NO: O15381

Subcellular Location: [Isoform 2]: Nucleus, nucleoplasm.; [Isoform 1]: Nucleus, nucleolus. Nucleus, nucleoplasm. Expressed predominantly in the nucleolus. Associates with pre-ribosomal particles in the nucleus.

Research Use Only