NXF3 rabbit pAb - ES6819

NXF3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6819-50, ES6819-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008],

Alternate Name: NXF3; TAPL3; Nuclear RNA export factor 3; TAP-like protein 3; TAPL-3

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human NXF3. AA range:72-121

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 60kD

Human Gene ID: 56000

Human SWISS Prot NO: Q9H4D5

Subcellular Location: Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm.

Research Use Only