Product Description

NY-CO-1 (K914) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2456-50, BS2456-100

Sizes: 50µl, 100µl

Swiss-Prot: O60524

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Protein names: Nuclear export mediator factor NEMF; Serologically defined colon cancer antigen 1; Gene names: NEMF; SDCCAG1. Function: Plays a role in nuclear export. Subunit structure: Interacts (via its N-terminus) with XPO1. Subcellular location: Nucleus.Tissue specificity: Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis. Domain: The N-terminal domain contains a nuclear export signal. The C-terminal domain may interact with cargo proteins. Miscellaneous: Active in normal lung tissue, but is inactive in several lung cancer cell lines.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: NY-CO-1 (K914) polyclonal antibody detects endogenous levels of NY-CO-1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of NY-CO-1 (K914) polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: PC12 whole cell lysate, Immunohistochemistry (IHC) analyzes of NY-CO-1 (K914) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 110 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Nuclear export mediator factor NEMF; Antigen NY-CO-1; Serologically defined colon cancer antigen 1; NEMF; SDCCAG1

Immunogen: Synthetic peptide, corresponding to amino acids 881-930 of Human NY-CO-1.

Conjugate: Unconjugated

Modification: Unmodified