NYX Polyclonal Antibody - E-AB-63160

NYX Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63160-60, E-AB-63160-120, E-AB-63160-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NYX

Target Synonym: NYX; CLRP; CSNB1; CSNB1A; CSNB4; NBM1

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9GZU5

Background: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human NYX (NP_072089.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only