OAS1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-90909-60, E-AB-90909-120, E-AB-90909-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: OAS1
Target Synonym: OAS1; E18/E16; IFI-4; OIAS; OIASI
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P00973
Background: This gene is induced by interferons and encodes a protein that synthesizes 2', 5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human OAS1
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 41kDa/43kDa/46kDa/47kDa
Observed MW: 46kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only