OAS2 Polyclonal Antibody - BT-AP06309

OAS2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06309-20, BT-AP06309-50, BT-AP06309-100

Citations, Manuals and MSDS Available upon request.

Background: OAS2 encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The 2'-5'-oligoadenylate synthetase 2 is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Areas: Immunology

Target Protein: OAS2

Applications: WB, IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: OAS2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 82431

UniProt Accession: Human: P29728; Mouse: E9Q9A9; Rat: Q5MYU0

Synonyms: OAS2; 2'-5'-oligoadenylate synthase 2; (2-5')oligo(A) synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS

GeneID: Human: 4939; Mouse: 246728; Rat: 363938

Research Use Only