Product Description

Occludin (A23) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: AP0765-50, AP0765-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Occludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellμlar loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regμlating both the localization and the function of occludin. Expression of occludin is up-regμlated by polyunsaturated fatty acids, increasing transendothelial cell resistance and reducing cellμlar permeability to large molecμles. The level of occludin varies greatly depending on tissue, in brain tissue, occludin is highly expressed at cell-cell contact sites.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: OCLN

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human Occludin.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Occludin (A23) polyclonal antibody detects endogenous levels of Occludin protein.

Molecular Weight: ~ 59 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q16625

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only