OCLN rabbit pAb - ES11811

OCLN rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11811-50, ES11811-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],

Source: Rabbit

Applications: WB IF; ELISA

Dilution: WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from part region of human protein. AA350-400

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 57kD

Human Gene ID: 100506658

Human SWISS Prot NO: Q16625

Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell junction, tight junction.

Research Use Only