Product Description

Oct-1 (L68) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS1260-50, BS1260-100

Sizes: 50µl, 100µl

Swiss-Prot: P14859

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from a wide range of tissues, where they function in the elimination of endogenous amines, cationic drugs and other xenobiotics. In humans, OCT1 is primarily expressed in the liver while OCT2 is expressed in the kidney. OCT3 is expressed in the placenta, skeletal muscle, prostate, aorta and liver. OCT3, also known as extraneuronal monoamine transporter, is widely expressed in different regions of the brain including the hippocampus, cerebellum and cerebral cortex. OCT3 mediates the uptake of several neuroactive agents, including dopamine, and may play an important role in the disposition of neurotransmitters and cationic neurotoxins in the brain.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: OCT (L68) polyclonal antibody detects endogenous levels of OCT1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Oct-1 (L68) polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate (40ug)
Lane 2: HepG2 whole cell lysate (40ug)
Lane 3: PC12 whole cell lysate (40ug)
Lane 4: NIH-3T3 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of OCT1 (L68) pAb in paraffin-embedded human lymph node tissue.

Bioworld Molecular Weight: ~ 89 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: POU domain, class 2, transcription factor 1; NF-A1; Octamer-binding protein 1; Oct-1; Octamer-binding transcription factor 1; OTF-1; POU2F1; OCT1; OTF1

Immunogen: Synthetic peptide, corresponding to amino acids 30-80 of Human Oct-1.

Conjugate: Unconjugated

Modification: Unmodified