OCT-4 Monoclonal Antibody - BT-MCA4717

OCT-4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4717-50, BT-MCA4717-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.

Research Areas: Others

Target Protein: OCT-4

Applications: WB, ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7E7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: OCT-4

Immunogen: Synthesized peptide derived from internal of human Oct4.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 45kDa

UniProt Accession: Q01860

Synonyms: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4, MGC22487, POU5F1

GeneID: 5460

Research Use Only