Product Description

OGG1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33775-50, RA33775-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: 8-oxoguanine DNA glycosylase (OGG1) Homo sapiens This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 37

Protein Molecular Weight (kDa): 37

Storage: -20°C/1 year

Human Gene ID: 4968

Human SwissProt Number: O15527

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only