OGG1 Polyclonal Antibody - RA33775

OGG1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33775-50, RA33775-100

Citations, Manuals and MSDS Available upon request.

Background: 8-oxoguanine DNA glycosylase (OGG1) Homo sapiens This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 4968

Protein MW (KDa): 37

SWISS: O15527

Source: Rabbit

Research Use Only