OGN Polyclonal Antibody-BS8348

OGN Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8348-50, BS8348-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P20774

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

All Applications: WB 1:500 - 1:2000
IHC 1:100 - 1:200
IF 1:50 - 1:200

Background: The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican, Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGFβ. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TFGβ1 or TGFβ2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: OGN polyclonal antibody detects endogenous levels of OGN protein.

Bioworld Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using OGN antibody., Immunohistochemistry of paraffin-embedded rat brain using OGN antibody at dilution of 1:100 (40x lens)., Immunohistochemistry of paraffin-embedded human stomach using OGN antibody at dilution of 1:100 (40x lens).

Alternative Name: Mimecan; Osteoglycin; Osteoinductive factor; OIF; OGN; OIF; SLRR3A

Immunogen: Recombinant full length Human OGN.

Conjugate: Unconjugated

Modification: Unmodified