OLR1 Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS7287-50, BS7287-100 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Swiss-Prot: P78380 Host: Rabbit Reactivity: Human, Rabbit, Rat Applications: WB, IHC ICC IF All Applications: WB=1:500-2000 IHC=1:100-500 ICC=1:100-500 IF=1:100-500 Background: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity: OLR1 polyclonal antibody detects endogenous levels of OLR1 protein. Bioworld Molecular Weight: ~ 50 kDa Note: For research use only, not for use in diagnostic procedure. Extra Notes: Sample: Cerebrum (Rat) Lysate at 40 ug Primary: Anti- LOX1 at 1/300 dilution, Sample:293T(Human) Cell Lysate at 30 ug Primary: Anti-LOX 1 at 1/300 dilution, Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LOX 1) Polyclonal Antibody, Unconjugated at 1:500 overnight at 4℃., Paraformaldehyde-fixed, paraffin embedded (Rabbit brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LOX 1) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4℃。 Alternative Name: Lectin-type oxidized LDL receptor 1; OLR1; lectin-like low density lipoprotein receptor-1; Oxidized low-density lipoprotein receptor 1; Ox-LDL receptor 1; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; LOX-1; BLOX1; Contains: Oxidized low-density lipoprotein receptor 1, soluble form A; Oxidized low-density lipoprotein receptor 1, soluble form B; OLR1_HUMAN. Immunogen: KLH conjugated synthetic peptide derived from rabbit LOX-1:201-273/273 Conjugate: Unconjugated Modification: Unmodified