OMG Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-16668-60, E-AB-16668-120, E-AB-16668-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: OMG
Target Synonym: Oligodendrocyte-myelin glycoprotein; Omg; OMGP; OMGP
Research Areas: Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P23515
Background: Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells; from dorsal root ganglion explants in which growth cone collapse was observed; from rat retinal ganglion neurons; and from NG108 and PC-12 cells.
Concentration: 0.4 mg/mL
Immunogen: Synthetic peptide of human OMG
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:25-1:100
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only