Product Description

OOEP Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90985-50, BS90985-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9CWE6

Host: Rabbit

Reactivity: Mouse

Applications: IHC

All Applications: IHC:1:200

Background: OOEP (oocyte-expressed protein homolog), also known as KHDC2 (KH homology domain-containing protein 2) or OEP19 (oocyte- and embryo-specific protein 19), is a 149 amino acid cytoplasmic protein that belongs to the KHDC1 family and contains one KH domain. As a member of the subcortical maternal complex (SCMC), OOEP is necessary for zygotes to progress beyond the first embryonic cell divisions. In addition to OOEP, the SCMC includes NALP5 and TLE6. The gene that encodes OOEP consists of approximately 26,579 bases and maps to human chromosome 6q13. With 170 million base pairs, chromosome 6 comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Purification and Purity: Peptide affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: OOEP polyclonal antibody detects endogenous levels of OOEP protein.

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodified

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded mouse ovary tissue using anti-OOEP antibody. Counter stained with hematoxylin.