Product Description

OPRL1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8068-50, BS8068-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Endogenous opioid peptides and opiates like morphine mediate their cellμlar effects through membrane bound receptors. Three different types of opioid receptors have been identified, mu-type, delta-type and kappa-type. A fourth opioid receptor, KOR-3 (kappa-type opioid receptor, also designated ORL1- Opioid Receptor Like 1), has been identified. Though closely related genetically to the other opioid receptors, KOR-3 has a distinct pharmacological profile. Nociceptin, the neuropeptide which activates KOR-3, is structurally similar to the kappa-opioid peptide dynorphin A, but quite different in its mode of interaction with its receptor. KOR-3 is widely expressed in the nervous system, and is likely to modμlate a broad range of physiological and behavioral functions.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Nociceptin receptor, Kappa-type 3 opioid receptor, KOR-3, Orphanin FQ receptor, OPRL1, OOR, ORL1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human OPRL1.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: OPRL1 polyclonal antibody detects endogenous levels of OPRL1 protein.

Molecular Weight: ~ 50 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P41146

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only