Product Description

Opticin Polyclonal Antibody

Catalogue Numbers: BS60333-50, BS60333-100

Sizes: 50µl, 100µl

Alternative Name: Oculoglycan; OPTC; OPT

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9UBM4

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Opticin polyclonal antibody detects endogenous levels of Opticin protein.

Bioworld Molecular Weight: ~ 40 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Opticin polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: Mouse heart tissue lysate
Lane 3: Rat heart tissue lysate

Immunogen: A synthetic peptide corresponding to residues in Human Opticin.

Conjugate: Unconjugated

Modification: Unmodified